LD-Letalna doza THC-a

[Narquila]

Poznato mi je da se ni jedan covijek na svijetu nije predozirao thc-om i bas me je zanimala kolika je to doza koju se treba uzeti odjednom da se usmrti covijek thc-om..

Evo sta sam nasao na wikipediji(sad ovo nisu mozda bas pouzdane informacije al pokazuje da je ne moguce se predozirati thc-om)



Toxicity

Main article: LD50 of THC


According to the Merck Index, 12th edition, THC has a LD50 value of 1270 mg/kg (male rats) and 730 mg/kg (female rats) administered orally dissolved in sesame oil.[4]

If this were scaled up to an adult human, the LD50 would be between approximately 86 g and 50 g for a 68-kg (150-lb) male or female person, respectively.[citation needed]This would be equivalent to 1-1.8 kg of cannabis with a 5% THC content (roughly average) taken orally. The LD50 value for rats by inhalation of THC is 42 mg/kg of body weight. It is important to note, however, that toxicity in animal models does not necessarily correlate to human toxicity. THC receptor distribution in the rat central nervous system is different from that of humans, meaning that there is the significant possibility that toxicity in humans varies from the published animal LD50 studies. There has never been a documented fatality from marijuana or THC overdose.[5] Absorption is limited by serum lipids, which can become saturated with THC, thus the inherent solubility may mitigate toxicity. In order to create a lethal overdose in a human, one would have to consume 1500 pounds in under 15 minutes,[6]

Studies of the distribution of the cannabinoid receptors in the brain explain why THC's toxicity is so low (i.e., the LD50 of the compound is so large): Parts of the brain that control vital functions such as respiration do not have many receptors, so they are relatively unaffected even by doses larger than could ever be ingested under any normal conditions.


Znaci treba uzeti 1-1.8kg trave koja sadrzi 5% thc-a (i to odjednom) da bi se predozirao..znaci predoziranje je nemoguce.
Prije ces se ubiti vodom neg thc-om

[elephant0r]

ccc... pa doso si do krivog zakljucka...
procitaj clanak jos jednom!!

Absorption is limited by serum lipids, which can become saturated with THC, thus the inherent solubility may mitigate toxicity. In order to create a lethal overdose in a human, one would have to consume 1500 pounds in under 15 minutes.

1500 pani je 681.8 kg

[gloSS_ZelenKy]

http://forums.vutra.org/medicina/106...-doza-thc.html

Uživajte :D

[Narquila]

Uuupsss Gloss ja se izvinjavam...

Nisam to ti je doza u 15 minuta a ona je odjednom

[m1k4c]

evo mozete da posaljete kombi da isprobamo na meni
dajte svoj doprinos medicini

[High Times]

smrtonosno je i 50kg ako ti padne na glavu iako bi puno njih volilo da se to dogodi,a 1g je zivotonosan

[SkolskiOne]

ja bi isto da se na meni testira letalna doza:) ako ima zainteresiranih,ima nas tu par voljnih,pušit čemo dok ne postanemo pršuti:)) a možemo i jest sa čokoladom,ma svakako!!!!

[DirtyDeeds]

Hmmm......kad bi nekako uspio nastavit pušiti jakooooooo dugo bez prestanka.....nekak mislim da bi umro,ne od THC-a nego od nekog otrova iz dima.

[elephant0r]

Da Dirty, ali pusenje je samo jedan od nacina konzumiranja tako da se ne uzima kao referenca.

[SkolskiOne]

da pušiš konstatno umro bi od trovanja ugljičnim monoksidom,al zato je tu papanje u različitim oblicima:kolačići,čokolade,torte,šejkovi..ma šta god ti mašta poželi,ako si baš pohlepan možeš jest i solo vrhece,dok se ne predoziraš:)))eheeh skoro!ako si nilski konj možda, pa možeš staviti 680kila vutre u sebe...

[THC mind]

sve u prevelikim dozama je stetno
da se razumijemo